[角膜缘上皮自体移植治疗翼状胬肉]

[Limbal epithelial autograft transplantation in treatment of pterygium].

作者信息

Du Zhenya, Jiang Deyong, Nie Aiguang

机构信息

Department of Ophthalmology, The Second Affiliated Hospital, Xiangya Medical College of Center South University, Changsha 410011, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2002 Jun;38(6):351-4.

PMID:12139812

Abstract

OBJECTIVE

To observe the therapeutic effects of limbal epithelial autograft transplantation and pterygium excision in the treatment of pterygium.

METHODS

A prospective randomized paired-eye trial was studied. There were 208 patients (229 eyes) with initial pterygium, and they were allocated to two groups: excision of pterygium with limbal epithelial autograft transplantation surgery (A group, 106 cases and 124 eyes) and simple pterygium excision (B group, 102 cases and 105 eyes). The criteria for recovery were corneal transparency with stable epithelial healing and no abnormal proliferation of pterygium-like tissue. The post-operative follow-up periods ranged from 18 approximately 28 (22.4 +/- 4.9) months.

RESULTS

Some of the patients lost follow-up. In the eyes followed up, 5 of 11 2 eyes (4.5%) in A group and 41 of 96 eyes (42.7%) in B group were recurred, the difference being very significant (P < 0.001).

CONCLUSION

To provide a new stem cell source, limbal epithelial autograft transplantation, for an injured limb us is a reasonable therapeutic method for the treatment of pterygium.

摘要

目的

观察自体角膜缘上皮移植联合翼状胬肉切除术治疗翼状胬肉的疗效。

方法

采用前瞻性随机配对眼试验。选取初发性翼状胬肉患者208例（229眼），分为两组：自体角膜缘上皮移植联合翼状胬肉切除术（A组，106例124眼）和单纯翼状胬肉切除术（B组，102例105眼）。以角膜透明、上皮愈合稳定且无翼状胬肉样组织异常增生为治愈标准。术后随访时间为18至28（22.4±4.9）个月。