Xi Xing-hua, Jiang De-yong, Tang Luo-sheng
Department of Ophthalmology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Hunan Yi Ke Da Xue Xue Bao. 2003 Apr;28(2):149-51.
To evaluate the curative effects of amniotic membrane transplantation and amniotic membrane combined with limbal autograft on patients of complicated pterygium.
Forty-two cases (48 eyes) of recurrent pterygium or pseudopterygium were operated on with human amniotic membrane transplantation (20 cases 22 eyes) and amniotic membrane combined with limbal autograft (22 cases 26 eyes). All cases were followed up for 6-12 months.
In 2 week postoperation, corneal wound recovered quickly and cured by epithelium except two eyes in amniotic membrane combined with limbal autograft group, but 8 eyes were not cured in amniotic membrane transplantation group. There was significant difference between two groups (P < 0.05). In the terms of follow-up, no rejection or recurrence were found in amniotic membrane with limbal autograft group, but 3 eyes recurred a relapse in amniotic membrane transplantation group.
Amniotic membrane combined with limbal autograft is more effective in the treatment of recurrence or pseudopterygium than amniotic membrane transplantation, and is able to inhibit fibrosis, reconstruct the ocular surface and promote the epithelial recovery, so as to improve the curative effect and decrease the recurrence.
评估羊膜移植术以及羊膜联合自体角膜缘移植术治疗复杂性翼状胬肉患者的疗效。
对42例（48眼）复发性翼状胬肉或假性胬肉患者行手术治疗，其中20例（22眼）采用人羊膜移植术，22例（26眼）采用羊膜联合自体角膜缘移植术。所有病例随访6 - 12个月。
术后2周，除羊膜联合自体角膜缘移植组有2只眼外，其余角膜伤口愈合快且上皮化，而羊膜移植组有8只眼未愈合。两组间差异有统计学意义（P < 0.05）。随访期间，羊膜联合自体角膜缘移植组未发现排斥或复发，但羊膜移植组有3只眼复发。
羊膜联合自体角膜缘移植术治疗复发性或假性胬肉比羊膜移植术更有效，并能抑制纤维化、重建眼表及促进上皮修复，从而提高疗效并降低复发率。
