Chung Darryl A, Sharples Linda D, Nashef Samer A M
Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge CB3 8RE, UK.
Eur J Cardiothorac Surg. 2002 Aug;22(2):282-6. doi: 10.1016/s1010-7940(02)00303-2.
To identify predictors of requirement for readmission to the intensive care unit (ICU) for patients undergoing cardiac surgery.
The setting was a 17-bedded ICU in a tertiary level institute for specialist adult cardiorespiratory disease. The case notes and ICU charts of 65 ICU readmissions and 65 controls, matched for day of initial ICU discharge, were analysed. Patient variables assessed included preoperative risk stratification, ICU admission APACHE III score and intensive therapy interventions, complications and indication for readmission if readmitted.
Twenty of 65 patients (31%) readmitted to the cardiac ICU died, compared with no mortality among the control group. Significant univariate determinants of ICU readmission (odds ratio, 95% confidence interval) included worse angina (1.38, 0.99-1.91) and dyspnoea (1.70, 1.10-2.61) classes and corresponding non-elective surgery (2.04, 1.31-3.19), higher Parsonnet score (1.06, 1.01-1.11) or EuroSCORE (1.14, 1.01-1.28), APACHE III score (1.03, 1.00-1.05), body mass index>27 (4.25, 1.43-12.63), non-usage of beta-blockers (1.53, 1.03-2.26), emergency resternotomy (5.00, 1.10-22.79), and lower haemoglobin (0.75, 0.58-0.96), higher required inspiratory oxygen (1.05, 1.02-1.08), and higher respiratory rate upon ICU discharge (1.09, 1.01-1.18). Renal failure, respiratory failure and cardiac arrest were the most common indications for ICU readmission. Thirty-five of 65 patients readmitted to the ICU required ventilation for a mean of 7.1 days. The mean ICU readmission duration for all 65 cases was 5.7 days.
Readmission of cardiac surgical patients to the ICU is associated with high morbidity and mortality, and substantial resource consumption. Parsonnet or EuroSCORE risk stratification models in combination with obesity, operative urgency, resternotomy and respiratory indices at time of intended ICU discharge are strongly associated with readmission to ICU.
确定心脏手术患者再次入住重症监护病房(ICU)的预测因素。
研究地点为一所治疗成人专科心肺疾病的三级机构中设有17张床位的ICU。分析了65例再次入住ICU患者及65例对照患者(根据首次从ICU出院日期匹配)的病历和ICU图表。评估的患者变量包括术前风险分层、入住ICU时的急性生理与慢性健康状况评分系统(APACHE)III评分、强化治疗干预措施、并发症以及再次入住时的再次入住指征。
65例再次入住心脏ICU的患者中有20例(31%)死亡,而对照组无死亡病例。ICU再次入住的显著单因素决定因素(比值比,95%置信区间)包括更严重的心绞痛(1.38,0.99 - 1.91)和呼吸困难分级(1.70,1.10 - 2.61)以及相应的非择期手术(2.04,1.31 - 3.19)、更高的Parsonnet评分(1.06,1.01 - 1.11)或欧洲心脏手术风险评估系统(EuroSCORE)评分(1.14,1.01 - 1.28)、APACHE III评分(1.03,1.00 - 1.05)、体重指数>27(4.25,1.43 - 12.63)、未使用β受体阻滞剂(1.53,1.03 - 2.26)、急诊再次胸骨切开术(5.00,1.10 - 22.79),以及更低的血红蛋白水平(0.75,0.58 - 0.96)、更高的所需吸入氧浓度(1.05,1.02 - 1.08)和ICU出院时更高的呼吸频率(1.09,1.01 - 1.18)。肾衰竭、呼吸衰竭和心脏骤停是ICU再次入住最常见的指征。65例再次入住ICU的患者中有35例需要机械通气,平均通气时间为7.1天。65例患者总的ICU再次入住时长平均为5.7天。
心脏手术患者再次入住ICU与高发病率、高死亡率以及大量资源消耗相关。Parsonnet或EuroSCORE风险分层模型,结合肥胖、手术紧迫性、再次胸骨切开术以及预期从ICU出院时的呼吸指标,与再次入住ICU密切相关。