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[荷兰全科医生学院实践指南“更年期”;妇产科领域的反应]

[The Dutch College of General Practitioners practice guideline 'The menopause'; reaction of the field of obstetrics and gynaecology].

作者信息

Hamerlynck J V Th H, Knuist M

机构信息

Academisch Medisch Centrum, afd. Verloskunde en Gynaecologie, Meibergdreef 9, 1105 AZ Amsterdam.

出版信息

Ned Tijdschr Geneeskd. 2002 Jul 13;146(28):1310-2.

Abstract

In the Dutch College of General Practitioners' (NHG) practice guideline on the menopause (which also covers hormone therapy), menopausal transition is considered as a physiological life process with inconveniences which can generally be settled by providing information, while leaving hormonal treatment for women who experience serious restrictions in their daily life as a consequence of vasomotor flushes or urogenital atrophy. In those cases, the guideline says, hormonal treatment should not be given for longer than three to six months, after which it should be stopped until a relapse arises. However, it usually takes at least six months of oestrogen replacement therapy to restore urogenital atrophy as well as for the woman to recover from its discomforts such as dyspareunia. Dosages of oestrogens in different hormonal therapies should be 50% or 25% of those advocated in the guideline, as the lowest effective dosage of oestrogen is sufficient. More generally, a woman affected by menopausal inconveniences is not a patient. She deserves to decide for herself whether or not she is willing to use hormone replacement therapy, and if so, she should be allowed to decide on the duration of hormone treatment. The physician should provide adequate information and benevolent supervision.

摘要

在荷兰全科医生学院(NHG)关于更年期的实践指南(其中也涵盖激素疗法)中,更年期过渡被视为一个伴有不便之处的生理生命过程,这些不便通常可通过提供信息来解决,而激素治疗则适用于那些因血管舒缩性潮红或泌尿生殖系统萎缩而在日常生活中受到严重限制的女性。该指南指出,在这些情况下,激素治疗不应超过三至六个月,之后应停药,直至复发。然而,通常至少需要六个月的雌激素替代疗法才能恢复泌尿生殖系统萎缩,以及让女性从诸如性交困难等不适中恢复过来。不同激素疗法中的雌激素剂量应为指南中所倡导剂量的50%或25%,因为最低有效剂量的雌激素就足够了。更普遍地说,受更年期不便影响的女性并非患者。她有权自行决定是否愿意使用激素替代疗法,如果愿意,她应该能够决定激素治疗的持续时间。医生应提供充分的信息并给予善意的监督。

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