Tailor R C, Hanson W F
Department of Radiation Physics, The University of Texas, M.D. Anderson Cancer Center, Houston 77030, USA.
Med Phys. 2002 Jul;29(7):1464-72. doi: 10.1118/1.1487857.
Task Group 51 (TG51), of the Radiation Therapy Committee of the American Association of Physicists in Medicine (AAPM), has developed a calibration protocol for high-energy photon and electron therapy beams based on absorbed dose standards. This protocol is intended to replace the air-kerma based protocol developed by an earlier AAPM task group (TG21). Conversion to the newer protocol introduces a change in the determined absorbed dose. In this work, the change in dose is expressed as the ratio of the doses (TG51/TG21) based on the two protocols. Dose is compared at the TG-51 reference depths of 10 cm for photons and d(ref) for electrons. Dose ratios are presented for a variety of ion chambers over a range of photon and electron energies. The TG51/TG21 dose ratios presented here are based on the dosimetry factors provided by the two protocols and the chamber-specific absorbed dose and exposure calibration factors (N60Co(D,w) and Nx) provided by the Accredited Dosimetry Calibration Laboratory (ADCL) at The University of Texas, M. D. Anderson Cancer Center (MDACC). As such, the values presented here represent the expected discrepancies between the two protocols due only to changes in the dosimetry parameters and the differences in chamber-specific dose and air-kerma standards. These values are independent of factors such as measurement uncertainties, setup errors, and inconsistencies arising from the mix of different phantoms and ion chambers for the two protocols. Therefore, these ratios may serve as a guide for institutions performing measurements for the switch from TG21-to-TG51 based calibration. Any significant deviation in the ratio obtained from measurements versus those presented here should prompt a review to identify possible errors and inconsistencies. For all cylindrical chambers included here, the TG51/TG21 dose ratios are the same within +/-0.6%, irrespective of the make and model of the chamber, for each photon and electron beam included. Photon beams show the TG51/TG21 dose ratios decreasing with energy, whereas electrons exhibit the opposite trend. The dose ratio for photons is near 1.00 at 18 mV increasing to near 1.01 at 4 mV while the dose ratio for electrons is near 1.02 at 20 MeV decreasing only 0.5% to near 1.015 at 6 MeV. For parallel-plate chambers, the situation is complicated by the two possible methods of obtaining calibration factors: through an ADCL or through a cross-comparison with a cylindrical chamber in a high-energy electron beam. For some chambers, the two methods lead to significantly different calibration factors, which in turn lead to significantly different TG51/TG21 results for the same chamber. Data show that if both N60Co(D,w) and Nx are obtained from the same source, namely an ADCL or a cross comparison, the TG51/TG21 results for parallel-plate chambers are similar to those for cylindrical chambers. However, an inconsistent set of calibration factors, i.e., using N60Co(D,w) x k(ecal) from an ADCL but Ngas from a cross comparison or vice versa, can introduce an additional uncertainty up to 2.5% in the TG51/TG21 dose ratios.
美国医学物理师协会(AAPM)放射治疗委员会的任务组51(TG51),已基于吸收剂量标准制定了高能光子和电子治疗束的校准方案。该方案旨在取代AAPM早期任务组(TG21)制定的基于空气比释动能的方案。转换到新方案会导致所确定的吸收剂量发生变化。在本研究中,剂量变化表示为基于两种方案的剂量比(TG51/TG21)。在光子的10 cm和电子的d(ref)的TG - 51参考深度处比较剂量。给出了一系列光子和电子能量范围内各种电离室的剂量比。这里给出的TG51/TG21剂量比基于两种方案提供的剂量学因子以及德克萨斯大学MD安德森癌症中心(MDACC)认可剂量校准实验室(ADCL)提供的特定电离室吸收剂量和照射校准因子(N60Co(D,w)和Nx)。因此,这里给出的值仅代表由于剂量学参数变化以及特定电离室剂量和空气比释动能标准差异导致的两种方案之间的预期差异。这些值与测量不确定度、设置误差以及因两种方案中不同模体和电离室混合产生的不一致性等因素无关。因此,这些比值可为从基于TG21校准转换到基于TG51校准进行测量的机构提供指导。测量得到的比值与这里给出的比值有任何显著偏差都应促使进行审查以识别可能的误差和不一致性。对于这里包含的所有圆柱形电离室,对于所包含的每个光子和电子束,TG51/TG21剂量比在±0.6%范围内相同,与电离室的品牌和型号无关。光子束的TG51/TG21剂量比随能量降低,而电子则呈现相反趋势。光子的剂量比在18 MV时接近1.00,在4 MV时增加到接近1.01,而电子的剂量比在20 MeV时接近1.02,在6 MeV时仅降低0.5%至接近1.015。对于平行板电离室,获取校准因子有两种可能的方法,这使情况变得复杂:通过ADCL或通过在高能电子束中与圆柱形电离室进行交叉比较。对于某些电离室,这两种方法会导致显著不同的校准因子,进而导致同一电离室的TG51/TG21结果显著不同。数据表明,如果N60Co(D,w)和Nx都从同一来源获得,即ADCL或交叉比较,平行板电离室的TG51/TG21结果与圆柱形电离室的结果相似。然而,一组不一致的校准因子,即使用来自ADCL的N60Co(D,w)×k(ecal)但来自交叉比较的Ngas,反之亦然,会在TG51/TG21剂量比中引入高达2.5%的额外不确定度。