由新真菌物种眼生肉盘菌引起的角膜溃疡。
Corneal ulcer caused by the new fungal species Sarcopodium oculorum.
作者信息
Guarro Josep, Höfling-Lima Ana Luisa, Gené Josepa, De Freitas Denise, Godoy Patricio, Zorat-Yu Maria Luisa, Zaror Luis, Fischman Olga
机构信息
Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, 43201 Reus, Tarragona, Spain.
出版信息
J Clin Microbiol. 2002 Aug;40(8):3071-5. doi: 10.1128/JCM.40.8.3071-3075.2002.
We describe a case of keratitis caused by a new species of the hyphomycetous genus Sarcopodium, S. oculorum. The corneal ulcer developed after 5 months of treatment with corticosteroids in a Brazilian boy diagnosed with allergic conjunctivitis. Fungal hyphae and conidia were detected in corneal scrapings, and repeated cultures were positive for this fungus. The infection was resolved with natamycin and ketoconazole. Eleven antifungals were tested against this fungus, and all except flucytosine and fluconazole showed in vitro activity.
我们描述了一例由丝孢菌属新物种眼丝孢菌（Sarcopodium oculorum）引起的角膜炎病例。一名被诊断为过敏性结膜炎的巴西男孩在接受皮质类固醇治疗5个月后出现角膜溃疡。在角膜刮片中检测到真菌菌丝和分生孢子，该真菌的重复培养均呈阳性。使用那他霉素和酮康唑后感染得到解决。对该真菌测试了11种抗真菌药，除氟胞嘧啶和氟康唑外，其他药物均显示出体外活性。
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