硫酸镁治疗早产期间的乳房胀痛和溢乳

Breast engorgement and galactorrhea during magnesium sulfate treatment of preterm labor.

作者信息

Lurie Samuel, Rotmensch Sigi, Feldman Noa, Glezerman Marek

机构信息

Department of Obstetrics and Gynecology, Wolfson Medical Center, Holon, Israel.

出版信息

Am J Perinatol. 2002 Jul;19(5):239-40. doi: 10.1055/s-2002-33086.

DOI:10.1055/s-2002-33086

PMID:12152141

Abstract

Breast engorgement and galactorrhea occasionally occur during tocolysis with ritodrine. We are not aware of breast engorgement and galactorrhea associated with other tocolytics. We report the first case of breast engorgement and galactorrhea during tocolysis with intravenous magnesium sulfate in a generally healthy 24-year-old woman admitted for tocolysis at 30 weeks' gestation. Breast engorgement and galactorrhea gradually subsided after magnesium sulfate was discontinued. The rapid disappearance of both the galactorrhea and the breast engorgement after discontinuation of magnesium sulfate treatment suggests a cause-effect relationship, the mechanism of which remains unclear.

摘要

在使用利托君进行保胎治疗期间，偶尔会出现乳房胀痛和溢乳现象。我们尚未发现其他保胎药物会引发乳房胀痛和溢乳。本文报告了首例在保胎治疗期间出现乳房胀痛和溢乳的病例，患者为一名24岁、孕期30周、身体健康的女性，当时正在接受静脉输注硫酸镁进行保胎治疗。停用硫酸镁后，乳房胀痛和溢乳症状逐渐消退。硫酸镁治疗停止后，溢乳和乳房胀痛迅速消失，提示二者之间存在因果关系，但其机制尚不清楚。