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[百草枯中毒与活性炭血液灌流]

[Paraquat poisoning and hemoperfusion with activated charcoal].

作者信息

López Lago A M, Rivero Velasco C, Galban Rodríguez C, Mariño Rozados A, Piñeiro Sande N, Ferrer Vizoso E

机构信息

Servicio de Medicina Intensiva, Hospital Clínico Universitario de Santiago de Compostela.

出版信息

An Med Interna. 2002 Jun;19(6):310-2.

Abstract

Paraquat is a common herbicide in Spain. In our country there are a few cases of this intoxication and it presents a high mortality even if the patients ingest a minimal amount. We present two cases of accidental poisoning with paraquat. These patients were admitted three hours after ingestion of toxin. They were treated with with orogastric lavage, activated charcoal, N-acetylcysteine, Fuller's earth, cathartics, support measures and hemoperfusion with activated charcoal. With these treatments both patients had a undetectable levels of paraquat 48 hours after and improvement of their symptoms, gastric and intestinal predominantly . We present the graphics of evolution of the plasma and urine levels of paraquat in both patients. We review the different aspects of treatment and update of this poisoning.

摘要

百草枯是西班牙一种常见的除草剂。在我国,这种中毒病例较少,即便患者摄入极少量百草枯也会有很高的死亡率。我们报告两例百草枯意外中毒病例。这些患者在摄入毒素三小时后入院。他们接受了经口胃灌洗、活性炭、N - 乙酰半胱氨酸、富勒土、泻药、支持措施以及活性炭血液灌流治疗。经过这些治疗,两名患者在48小时后百草枯水平检测不到,症状得到改善,主要是胃肠道症状。我们展示了两名患者血浆和尿液中百草枯水平的变化图表。我们回顾了这种中毒治疗的不同方面及最新情况。

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