Gross Allan E
Division of Orthopedic Surgery, University of Toronto, Mount Sinai Hospital, Ontario, Canada.
J Knee Surg. 2002 Summer;15(3):167-9.
The factors to be considered in selecting a technique are the diameter of the chondral defect, the depth of the bone defect, and the knee alignment. As a rough guide, I suggest the following guide to treatment. Chondral defects (without bone involvement) <3 cm in diameter can be treated with microfracture, autologous chondrocyte transplantation, osteochondral autografts, or periosteal grafts. Osteochondral defects <3 cm in diameter and 1 cm in bone depth can be treated with autologous chondrocyte transplantation, osteochondral autografts, or periosteal grafts. Articular defects >3 cm in diameter and 1 cm in bone depth require osteochondral allografts. This is a rough guide to treatment and only the opinion of the author. The greater the bone involvement and the less contained the defect, the greater the need for allograft tissue. Allograft tissue should, however, only be used when the size of the lesion is beyond the other techniques. For all of these techniques, realignment osteotomy should be performed as an adjunct procedure if the lesion is in a compartment under more than physiological compression.
选择治疗技术时需要考虑的因素包括软骨缺损的直径、骨缺损的深度以及膝关节对线情况。作为一个大致的指导,我建议如下治疗指南。直径小于3厘米的软骨缺损(无骨受累)可采用微骨折、自体软骨细胞移植、自体骨软骨移植或骨膜移植进行治疗。直径小于3厘米且骨深度为1厘米的骨软骨缺损可采用自体软骨细胞移植、自体骨软骨移植或骨膜移植进行治疗。直径大于3厘米且骨深度为1厘米的关节缺损需要同种异体骨软骨移植。这只是一个大致的治疗指南,仅为作者的观点。骨受累程度越高且缺损越不局限,对同种异体移植组织的需求就越大。然而,同种异体移植组织仅应在病变大小超出其他技术的适用范围时使用。对于所有这些技术,如果病变位于承受超过生理压力的关节间室,则应作为辅助手术进行截骨矫形。