Mixed model for analyzing geographic variability in mortality rates.

"A mixed model is proposed for the analysis of geographic variability in mortality rates. In addition to demographic parameters and random geographic parameters, the model includes additional random-effects parameters to adjust for extra-Poisson variability. The model uses a gamma-Poisson distribution with a random scale parameter having an inverse gamma prior. An empirical Bayes approach is used to estimate relative risks for geographic regions and annual rates for demographic groups within each region. Lung cancer in Missouri is used to motivate and illustrate the procedure."