Ofori-Nkansah N, Weissenfels I, Pribilla W
Schweiz Med Wochenschr. 1975 Oct 11;105(41):1319-24.
The course of spontaneous vitamin B6 deficiency anemia in a 57-year-old woman is reported. The anemia was characterized by hypochromasia of the erythrocytes, hyperferricemia, absence of hemolysis, and hyperplastic, ineffective, sideroblastic erythropoiesis of the bone marrow. It was corrected by oral vitamin B6 therapy. On interruption of the vitamin B6 therapy the anemia relapsed. On resumption of vitamin B6 medication it responded again with normalization of the hemoglobin and erythrocytes values. The hematological remission could be maintained under longterm vitamin B6 medication. The nosological significant of this rare anemia and its differentiation from other forms of anemia are discussed.
报告了一名57岁女性自发性维生素B6缺乏性贫血的病程。该贫血的特征为红细胞低色素、高铁血症、无溶血以及骨髓增生性、无效性、铁粒幼细胞性红细胞生成。口服维生素B6治疗可纠正该贫血。停用维生素B6治疗后贫血复发。重新开始服用维生素B6药物后，血红蛋白和红细胞值再次恢复正常。长期服用维生素B6药物可维持血液学缓解。讨论了这种罕见贫血的病因学意义及其与其他贫血形式的鉴别。
