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季节性与酒精使用之间的关系:一种遗传学假设。

Relationships between seasonality and alcohol use: a genetic hypothesis.

作者信息

Sher Leo

出版信息

Med Hypotheses. 2002 Jul;59(1):85-8. doi: 10.1016/s0306-9877(02)00130-5.

Abstract

Seasonal changes in mood and behavior (seasonality) are common throughout the population. Alcohol use and alcohol-related problems are also very common in society. Recent data suggest that seasonality is closely related to alcoholism. Some patients with alcoholism have a seasonal pattern to their alcohol abuse. Patients with alcoholism may be self-medicating an underlying seasonal affective disorder (SAD) with alcohol or manifesting a seasonal pattern to alcohol-induced depression. Family studies also suggest that there is a relationship between alcoholism and SAD. The author proposes that there is a genetic link between seasonality and alcoholism. This relationship is complex and involves various factors. It could be an inherited personality dimension, i.e., certain personality types may predispose to both seasonality and excessive alcohol consumption. SAD may be a subtype of mood disorder that is closely related to alcoholism. More studies are needed to better understand the mechanisms involved in the relationship between seasonality and alcohol use.

摘要

情绪和行为的季节性变化(季节性)在整个人口中很常见。饮酒及与酒精相关的问题在社会中也非常普遍。最近的数据表明,季节性与酒精中毒密切相关。一些酒精中毒患者的酗酒行为具有季节性模式。酒精中毒患者可能在用酒精自我治疗潜在的季节性情感障碍(SAD),或者表现出酒精所致抑郁的季节性模式。家族研究也表明酒精中毒与季节性情感障碍之间存在关联。作者提出季节性与酒精中毒之间存在遗传联系。这种关系很复杂,涉及多种因素。它可能是一种遗传的人格维度,即某些人格类型可能易患季节性变化和过度饮酒。季节性情感障碍可能是与酒精中毒密切相关的情绪障碍的一个亚型。需要更多研究来更好地理解季节性与饮酒之间关系所涉及的机制。

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