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酒精中毒与季节性情感障碍。

Alcoholism and seasonal affective disorder.

作者信息

Sher Leo

机构信息

Division of Neuroscience, Department of Psychiatry, Columbia University, New York, NY 10032, USA.

出版信息

Compr Psychiatry. 2004 Jan-Feb;45(1):51-6. doi: 10.1016/j.comppsych.2003.09.007.

Abstract

Seasonal changes in mood and behavior (seasonality) may be closely related to alcoholism. Some patients with alcoholism have a seasonal pattern to their alcohol misuse. They may be self-medicating an underlying seasonal affective disorder (SAD) with alcohol or manifesting a seasonal pattern to alcohol-induced depression. Both genetic and environmental factors play a role in the etiology and pathogenesis of alcoholism and SAD, operating, at least in part, through the brain serotonergic system. Family and molecular genetic studies suggest that there may be a genetic link between seasonality and alcoholism. Certain environmental and social factors may contribute to the development of seasonality in patients with alcoholism. The fact that SAD and alcoholism may be comorbid shows the importance of a thorough diagnostic interview. Both mental health and drug and alcohol professionals should be provided with education to assist with appropriate identification, management, and referral of patients presenting with comorbid alcoholism and SAD.

摘要

情绪和行为的季节性变化(季节性)可能与酒精中毒密切相关。一些酒精中毒患者存在酒精滥用的季节性模式。他们可能在用酒精自我治疗潜在的季节性情感障碍(SAD),或者表现出酒精所致抑郁的季节性模式。遗传和环境因素在酒精中毒和SAD的病因及发病机制中均起作用,至少部分是通过大脑血清素能系统发挥作用。家庭和分子遗传学研究表明,季节性与酒精中毒之间可能存在遗传联系。某些环境和社会因素可能促使酒精中毒患者出现季节性变化。SAD和酒精中毒可能共病这一事实表明了进行全面诊断性访谈的重要性。应向心理健康以及药物和酒精专业人员提供培训,以帮助他们对同时患有酒精中毒和SAD的患者进行适当识别、管理和转诊。

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