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脊柱手术后发生脊柱硬膜外血肿的危险因素。

Risk factors for spinal epidural hematoma after spinal surgery.

作者信息

Kou J, Fischgrund J, Biddinger A, Herkowitz H

机构信息

Department of Orthopaedic Surgery, William Beaumont Hospital, Royal Oak, Michigan, USA.

出版信息

Spine (Phila Pa 1976). 2002 Aug 1;27(15):1670-3. doi: 10.1097/00007632-200208010-00016.

Abstract

STUDY DESIGN

A case-control retrospective analysis comparing patients who developed a postoperative spinal epidural hematoma with patients who did not develop this complication.

OBJECTIVES

To identify risk factors for the development of an epidural hematoma following spinal surgery.

SUMMARY OF BACKGROUND DATA

Neurologic deterioration following spinal surgery is a rare but devastating complication. Epidural hematomas should be suspected in the patient who demonstrates a new postoperative neurologic deficit. The risk factors that predispose a patient to a postoperative spinal epidural hematoma have not been identified.

METHODS

Patients who underwent spinal surgery at a single institution over a 10-year period were retrospectively reviewed. Twelve patients who demonstrated neurologic deterioration after surgery and required surgical decompression because of an epidural hematoma were identified. All cases involved lumber laminectomies. A total of 404 consecutive patients that underwent lumbar decompression and did not develop an epidural hematoma formed the control group. Factors postulated to increase the risk of postoperative spinal epidural hematoma were compared between the two groups using logistic regression.

RESULTS

Multilevel procedures (P = 0.037) and the presence of a preoperative coagulopathy (P < 0.001) were significant risk factors. Age, body mass index, perioperative durotomies, and postoperative drains were not statistically significant risk factors.

CONCLUSIONS

Patients who require multilevel lumbar procedures and/or have a preoperative coagulopathy are at a significantly higher risk for developing a postoperative epidural hematoma.

摘要

研究设计

一项病例对照回顾性分析,比较发生术后脊柱硬膜外血肿的患者与未发生该并发症的患者。

目的

确定脊柱手术后硬膜外血肿发生的危险因素。

背景数据总结

脊柱手术后神经功能恶化是一种罕见但具有毁灭性的并发症。对于出现新的术后神经功能缺损的患者,应怀疑有硬膜外血肿。尚未确定使患者易发生术后脊柱硬膜外血肿的危险因素。

方法

对在单一机构接受脊柱手术达10年的患者进行回顾性研究。确定了12例术后出现神经功能恶化且因硬膜外血肿需要手术减压的患者。所有病例均涉及腰椎椎板切除术。总共404例连续接受腰椎减压且未发生硬膜外血肿的患者组成对照组。使用逻辑回归比较两组之间假定会增加术后脊柱硬膜外血肿风险的因素。

结果

多节段手术(P = 0.037)和术前存在凝血功能障碍(P < 0.001)是显著的危险因素。年龄、体重指数、围手术期硬脊膜切开术和术后引流并非具有统计学意义的危险因素。

结论

需要进行多节段腰椎手术和/或术前有凝血功能障碍的患者发生术后硬膜外血肿的风险显著更高。

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