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外周血管疾病作为冠状动脉旁路移植术后预后的预测指标

Peripheral vascular disease as predictor of outcome after coronary artery bypass grafting.

作者信息

Loponen P, Taskinen P, Laakkonen E, Nissinen J, Peltola T, Wistbacka J O, Luther M

机构信息

Department of Surgery, Vaasa Central Hospital, Finland.

出版信息

Scand J Surg. 2002;91(2):160-5. doi: 10.1177/145749690209100205.

Abstract

BACKGROUND AND AIMS

Understanding and objective assessment of risks is crucial in cardiac surgery. The aim of this study was to assess the influence of peripheral vascular disease (PVD) on morbidity, mortality and outcome in coronary artery bypass grafting (CABG) patients.

MATERIAL AND METHODS

The ankle-brachial pressure index (ABPI) was used as indicator of PVD and was measured in 178 CABG patients. Two groups were established: 1. normal ABPI (0.9-1.3) (n = 136) and 2. lowered ABPI (< 0.9) (n = 35). The mean follow-up was 26 months.

RESULTS

The presence of PVD was 20.5 %. Patients with PVD were older (p < 0.05), more often of female sex (p < 0.05), had higher Higgins's risk score (p = 0.001) and more often intermittent claudication (IC) (p < 0.001). PVD significantly predicted atrial fibrillation (FA) (p < 0.05) and relatively postoperative myocardial infarction (MI) (p = 0.058).

CONCLUSIONS

The presence of PVD is relatively high in CABG patients and increases with age. PVD predicts some morbidity but seems to have fairly little influence on short-term or middle-term outcome of CABG patients. ABPI may be of only limited value in identifying patients with high operative risk in CABG.

摘要

背景与目的

在心脏手术中,对风险的理解和客观评估至关重要。本研究的目的是评估外周血管疾病(PVD)对冠状动脉旁路移植术(CABG)患者发病率、死亡率及预后的影响。

材料与方法

采用踝臂压力指数(ABPI)作为PVD的指标,对178例CABG患者进行测量。设立两组:1. ABPI正常(0.9 - 1.3)(n = 136);2. ABPI降低(< 0.9)(n = 35)。平均随访时间为26个月。

结果

PVD的发生率为20.5%。患有PVD的患者年龄更大(p < 0.05),女性更多(p < 0.05),Higgins风险评分更高(p = 0.001),间歇性跛行(IC)更常见(p < 0.001)。PVD显著预测房颤(FA)(p < 0.05)和相对术后心肌梗死(MI)(p = 0.058)。

结论

CABG患者中PVD的发生率相对较高,且随年龄增加。PVD可预测一些发病率,但对CABG患者的短期或中期预后影响似乎较小。ABPI在识别CABG手术高风险患者方面可能价值有限。

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