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肝脏炎性假瘤的诊断

Diagnosis of inflammatory pseudotumor of the liver.

作者信息

Sakai Takahisa, Shiraki Katsuya, Yamamoto Norihiko, Kawakita Tomoyuki, Ohmori Shigeru, Itoh Iori, Nakano Takeshi, Yasuda Masayo, Yamakado Koichirou, Takeda Kan, Yagi Shintaro, Yamagiwa Kentaro, Yokoi Hajime, Noguchi Takashi, Uemoto Shinji

机构信息

First Department of Internal Medicine, Mie University School of Medicine, Tsu, Japan.

出版信息

Int J Mol Med. 2002 Sep;10(3):281-5.

Abstract

Inflammatory pseudotumor (IPT) is a rare benign tumor of unknown origin, it has the appearance of a malignant tumor but has a benign histology and clinical course. Therefore, we studied five patients with IPT of the liver to determine what examination can aid in its diagnosis. Five cases of inflammatory pseudotumor of the liver were analyzed. All patients were examined by echography, computed tomography (CT), magnetic resonance imaging (MRI), endoscopic retrograde cholangiography (ERC) and angiography to diagnose the liver tumor. In all patients echography and CT scan showed a similar appearance while MRI showed a variable pattern. In two patients ERC showed a stenotic image of intra-hepatic bile ducts. In the angiographic study, the arterial phase in three patients showed a hypervascular tumor and in one patient, a hypovascular tumor. Vascular abnormality was presented in one patient. Similarly, portography in four patients showed some abnormality. We performed ultrasonography-guided percutaneous needle biopsy in two patients in order to diagnose IPT. Histological examinations of two patients were consistent with IPT. The other three patients underwent surgical treatment for a cholangiocellular carcinoma or abscess. It is difficult to diagnose IPT of the liver exclusively with an image examination. Ultrasonography-guided percutaneous liver biopsy should be performed in order to diagnose IPT by histology.

摘要

炎性假瘤(IPT)是一种起源不明的罕见良性肿瘤,它具有恶性肿瘤的外观,但组织学和临床过程为良性。因此,我们研究了5例肝脏IPT患者,以确定何种检查有助于其诊断。分析了5例肝脏炎性假瘤病例。所有患者均接受了超声检查、计算机断层扫描(CT)、磁共振成像(MRI)、内镜逆行胆管造影(ERC)和血管造影以诊断肝脏肿瘤。所有患者中,超声检查和CT扫描表现相似,而MRI表现各异。2例患者的ERC显示肝内胆管狭窄影像。血管造影研究中,3例患者动脉期显示肿瘤血管丰富,1例患者显示肿瘤血管减少。1例患者出现血管异常。同样,4例患者的门静脉造影显示有一些异常。我们对2例患者进行了超声引导下经皮肝穿刺活检以诊断IPT。2例患者的组织学检查结果与IPT相符。另外3例患者因胆管细胞癌或肝脓肿接受了手术治疗。仅通过影像学检查很难诊断肝脏IPT。应进行超声引导下经皮肝穿刺活检,以便通过组织学诊断IPT。

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