Ludwig K, Bernhardt J, Steffen H, Lorenz D
Department of Surgery, Klinikum Suedstadt Rostock, Suedring 81, D-18059 Rostock, Germany.
Surg Endosc. 2002 Jul;16(7):1098-104. doi: 10.1007/s00464-001-9183-6. Epub 2002 Apr 9.
In the present study we examined, in a meta-analysis of the literature, the contribution of intraoperative cholangiography (IOC) to incidence, type, and time of diagnosis of common bile duct (CBD) injuries during laparoscopic cholecystectomy (LC).
Forty of 2104 reports were enrolled for analysis. In 26 reports we found exact information on type, location and repair of 405 major injuries and in a subgroup examination we selected 103 major injuries with detailed information as to the event and size of CBD injury in association with IOC.
The main incidence of CBD injuries was 0.36%. Using the method of routine IOC the incidence was 0.21% and the rate of diagnosis at the time of cholecystectomy 87% in contrast to selective use of IOC with 0.43% and 44.5%. In 405 cases of major CBD injuries, severe injuries predominated in 83.9% of the cases. Reconstruction with the help of a bilio-digestive anastomosis was necessary in 45.7% of all patients. In 34.8% of the cases a second intervention had to be made in the follow-up of 4 years after LC. The analysis of type, severity, recognition, and follow-up of CBD injuries during LC w/wo IOC showed significant advantages for doing routine IOC.
The use of IOC can avoid severe types of CBD injuries during LC, increase the recognition at the time operation, and influence the success of repair and outcome of the patients.
在本研究中,我们通过对文献的荟萃分析,探讨了术中胆管造影(IOC)对腹腔镜胆囊切除术(LC)期间胆总管(CBD)损伤的发生率、类型及诊断时间的影响。
从2104篇报告中选取40篇进行分析。在26篇报告中,我们获取了405例主要损伤的类型、位置及修复的确切信息,在亚组分析中,我们选取了103例主要损伤,这些损伤具有与IOC相关的CBD损伤事件及大小的详细信息。
CBD损伤的主要发生率为0.36%。采用常规IOC方法时,发生率为0.21%,胆囊切除时的诊断率为87%,相比之下,选择性使用IOC时的发生率为0.43%,诊断率为44.5%。在405例主要CBD损伤病例中,83.9%为严重损伤。45.7%的患者需要借助胆肠吻合术进行重建。34.8%的病例在LC术后4年的随访中需要进行二次干预。对有无IOC的LC期间CBD损伤的类型、严重程度、识别及随访分析显示,进行常规IOC具有显著优势。
使用IOC可避免LC期间严重类型的CBD损伤,提高手术时的识别率,并影响修复成功率及患者预后。