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[一例以左侧颞叶和顶叶萎缩为主的戈吉失语症病例]

[A case of Gogi aphasia with predominantly left temporal and parietal lobe atrophy].

作者信息

Wada Yuko, Nakagawa Yoshitsugu, Suenaga Toshihiko, Hashimoto Shuji

机构信息

Department of Neurology, Tenri Hospital, 200 Mishima, Tenri-shi, Nara 632-8552, Japan.

出版信息

No To Shinkei. 2002 Jun;54(6):507-11.

Abstract

We report a 68-year-old right-handed Japanese woman who had a history of progressive difficulty in understanding speech and naming. Neuropsychological examination presented Gogi (word meaning) aphasia and impairment of semantic memory for some common objects. She also presented acalculia and mild constructional impairment. There was no evidence of impairment in elementary perception and motor skills. Her memory performance of visual task was within normal range. She had neither personality change nor behavioral disorder. Magnetic resonance (MR) imaging showed atrophy in the left temporal lobe and the left parietal lobe. Single photon emission computed tomography (SPECT) scans demonstrated a decrease of regional cerebral blood flow in the atrophic sites and the left frontal lobe. We pointed out that the atrophy of the parietal lobe was atypical in the early stage of cortical degenerative disease presenting Gogi aphasia, in addition to in the light of classification of Fronto-Temporal Lobar Degeneration (FTLD).

摘要

我们报告了一名68岁的右利手日本女性,她有进行性言语理解和命名困难的病史。神经心理学检查显示为词义性失语以及对一些常见物体的语义记忆受损。她还存在失算症和轻度结构障碍。基本感知和运动技能没有受损的证据。她的视觉任务记忆表现处于正常范围。她既没有人格改变也没有行为障碍。磁共振成像显示左颞叶和左顶叶萎缩。单光子发射计算机断层扫描显示萎缩部位和左额叶的局部脑血流量减少。我们指出,鉴于额颞叶变性(FTLD)的分类,顶叶萎缩在出现词义性失语的皮质退行性疾病早期是不典型的。

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