Gundappa Rajaram K, Sud Kamal, Kohli Harbir S, Jha Vivekanand, Gupta Krishan L, Joshi Kusum, Sakhuja Vinay
Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ren Fail. 2002 May;24(3):369-72. doi: 10.1081/jdi-120005371.
Snakebite induced acute renal failure continues to occur in many tropical areas of the world. Renal histological lesions other than acute tubular necrosis and acute cortical necrosis as the cause of acute renal failure are rare. Only 3 cases of acute interstitial nephritis in patients with snakebite induced acute renal failure have been previously reported. We report a patient with acute renal failure following viperine snakebite due to acute interstitial nephritis. After a prolonged oliguric phase, there was complete recovery of renal function without institution of steroids. Interstitial nephritis may result from a hypersensitivity reaction to some component of the snake venom.
蛇咬伤所致急性肾衰竭在世界许多热带地区仍时有发生。除急性肾小管坏死和急性皮质坏死外，其他导致急性肾衰竭的肾脏组织学病变较为罕见。此前仅报道过3例蛇咬伤所致急性肾衰竭患者并发急性间质性肾炎的病例。我们报告1例因急性间质性肾炎导致蝰蛇咬伤后急性肾衰竭的患者。经过漫长的少尿期后，患者肾功能完全恢复，未使用类固醇药物。间质性肾炎可能是对蛇毒某些成分的过敏反应所致。
