腹腔镜下使用猪小肠黏膜下层进行疝修补术：一项初步研究。
Laparoscopic herniorrhaphy with porcine small intestinal submucosa: a preliminary study.
作者信息
Edelman David S
机构信息
The Gallbladder & Laparoscopic Surgery Center at Baptist Health System, Miami, FL 33176, USA.
出版信息
JSLS. 2002 Jul-Sep;6(3):203-5.
INTRODUCTION
Using mesh or a synthetic prosthesis during the laparoscopic repair of inguinal hernias has been demonstrated to be safe and effective. A new material, porcine small intestinal submucosa (SIS mesh), has been successfully used in canine and rodent animal models with excellent results. This mesh is degradable and resorbable with a marked decrease in the possibility of becoming infected. However, the amount of fibroblast ingrowth is equal to that with polypropylene mesh.
METHODS
A comparison was made between this new SIS mesh to repair 15 inguinal hernias in 12 patients and polypropylene mesh used in 12 similar patients. A preperitoneal approach with balloon dissection was used in all patients.
RESULTS
Demographics were similar in both groups. The results were excellent and compared equally. Complications (seroma, discomfort) were minimal in both groups and were similar.
CONCLUSIONS
Porcine small intestinal submucosa, SIS mesh, can be used for laparoscopic repair of inguinal hernias. Long-term follow-up will be necessary to confirm these preliminary results.
引言
在腹腔镜腹股沟疝修补术中使用补片或合成假体已被证明是安全有效的。一种新材料，猪小肠黏膜下层（SIS补片），已在犬类和啮齿类动物模型中成功使用，效果良好。这种补片可降解且可吸收，感染可能性显著降低。然而，成纤维细胞向内生长的数量与聚丙烯补片相同。
方法
对12例患者使用这种新型SIS补片修补15例腹股沟疝与12例类似患者使用聚丙烯补片的情况进行比较。所有患者均采用球囊分离的腹膜前入路。
结果
两组的人口统计学特征相似。结果均非常好，且相当。两组的并发症（血清肿、不适）均极少且相似。
结论
猪小肠黏膜下层，即SIS补片，可用于腹腔镜腹股沟疝修补术。需要长期随访以证实这些初步结果。
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