Soares Marcia Britto de Macedo, Moreno Ricardo Alberto, Moreno Doris Hupfeld
Mood Disorders Unit (GRUDA), Psiquiatric Institute, Hospital das Clínicas, Faculty of Medicine, University of São Paulo.
Rev Hosp Clin Fac Med Sao Paulo. 2002 Jan-Feb;57(1):31-8. doi: 10.1590/s0041-87812002000100006.
Electroconvulsive therapy is known to be effective in the treatment of mood disorders, more specifically for depression and mania. Although a large body of evidence confirms the efficacy of electroconvulsive therapy in the treatment of mania, few prospective studies have been done to assess its effectiveness in treatment-resistant manic episodes. These case reports describe the initial results of a study that is being conducted to evaluate the efficacy of Electroconvulsive therapy among treatment-resistant bipolar patients.
Three manic patients (according to DSM-IV criteria) who were considered treatment-resistant underwent a series of 12 bilateral Electroconvulsive therapy sessions. Before the treatment and then weekly, they were evaluated with the following rating scales: Young Mania Rating Scale, Hamilton Rating Scale for Depression, Brief Psychiatric Rating Scale, and Clinical Global Impressions-Bipolar Version.
The 3 patients showed a satisfactory response to Electroconvulsive therapy, although some differences in the course of response were observed.
These case reports suggest that Electroconvulsive therapy needs further evaluation for the treatment of resistant bipolar patients.
已知电休克治疗对心境障碍有效，更具体地说是对抑郁症和躁狂症有效。尽管大量证据证实电休克治疗对躁狂症有效，但很少有前瞻性研究评估其在难治性躁狂发作治疗中的有效性。这些病例报告描述了一项正在进行的研究的初步结果，该研究旨在评估电休克治疗在难治性双相情感障碍患者中的疗效。
三名被认为难治性的躁狂患者（根据DSM-IV标准）接受了一系列12次双侧电休克治疗。在治疗前以及随后每周，使用以下评定量表对他们进行评估：青年躁狂评定量表、汉密尔顿抑郁评定量表、简明精神病评定量表和临床总体印象-双相情感障碍版。
3名患者对电休克治疗显示出满意的反应，尽管在反应过程中观察到一些差异。
这些病例报告表明，电休克治疗在难治性双相情感障碍患者的治疗中需要进一步评估。
