全身性疾病中的瘙痒：机制与管理

Pruritus in systemic disease: mechanisms and management.

作者信息

Etter Lawrence, Myers Sarah A

机构信息

Division of Dermatology, Center for Aesthetic Services, Duke University Medical Center, 1300 Morreene Road, Durham, NC 27705, USA.

出版信息

Dermatol Clin. 2002 Jul;20(3):459-72, vi-vii. doi: 10.1016/s0733-8635(02)00011-6.

DOI:10.1016/s0733-8635(02)00011-6

PMID:12170879

Abstract

Pruritus is the most common symptom of skin disease. Even in the absence of primary cutaneous findings, severe and extensive pruritus often is associated with systemic disease. This review considers briefly the physiology of pruritus and discusses the various systemic diseases often accompanied by this bothersome symptom. In addition to exploring the possible mechanisms and potential therapies of itching in selected disorders, this review presents general recommendations for evaluating patients with unexplained pruritus and management guidelines for alleviating their discomfort.

摘要

瘙痒是皮肤病最常见的症状。即使没有原发性皮肤表现，严重且广泛的瘙痒通常也与全身性疾病有关。本综述简要探讨瘙痒的生理学，并讨论常伴有这种令人烦恼症状的各种全身性疾病。除了探讨特定疾病中瘙痒的可能机制和潜在治疗方法外，本综述还提出了评估不明原因瘙痒患者的一般建议以及缓解其不适的管理指南。