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髓母细胞瘤术中出血:一例病例报告及文献综述

Intraoperative hemorrhage in medulloblastoma: a case report and review of the literature.

作者信息

Fukai Junya, Uematsu Yuji, Shintani Aki, Nakai Kunio, Itakura Toru

机构信息

Department of Neurological Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, 641-0012 Japan.

出版信息

Childs Nerv Syst. 2002 Jul;18(6-7):356-60. doi: 10.1007/s00381-002-0601-4. Epub 2002 May 23.

Abstract

OBJECT

We present the first case of intraoperative hemorrhage in a medulloblastoma.

CASE REPORT

A 10-year-old girl presented with a 4-week history of headache, nausea, and vomiting. Radiological examination showed a space-occupying mass in the cerebellar vermis. Surgical removal was performed via a midline suboccipital approach. When the dura was incised and the occipital sinus was ligated after suboccipital craniectomy, bleeding occurred in the tumor. Macroscopically, hematoma was found only in the left part of the tumor and not in the right part. Microscopically, different architectures of tumor vessels, thin-walled and thick-walled, were found between the left part and the right part, respectively. The tumoral contents and hematoma were totally removed. Histological examination revealed a medulloblastoma.

CONCLUSION

We experienced a very rare case of medulloblastoma in which intratumoral hemorrhage occurred during operation. We speculate that ligation of the occipital sinus and thin-walled vessels within the tumor might have caused the hemorrhage in our case.

摘要

目的

我们报告了第一例髓母细胞瘤术中出血的病例。

病例报告

一名10岁女孩有4周的头痛、恶心和呕吐病史。影像学检查显示小脑蚓部有占位性肿块。通过枕下中线入路进行手术切除。枕下开颅术后切开硬脑膜并结扎枕窦时,肿瘤内发生出血。肉眼可见,血肿仅出现在肿瘤的左侧部分,右侧未见。显微镜下,肿瘤血管的结构不同,左侧为薄壁血管,右侧为厚壁血管。肿瘤内容物和血肿被完全清除。组织学检查显示为髓母细胞瘤。

结论

我们遇到了一例非常罕见的髓母细胞瘤病例,术中发生了肿瘤内出血。我们推测,在我们的病例中,枕窦结扎和肿瘤内薄壁血管可能导致了出血。

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