Romanov V A
Zh Mikrobiol Epidemiol Immunobiol. 1975 Jul(7):59-64.
Experiments were conducted on rabbits; primary and secondary administration of staphylococcus vaccine was regularly accompanied by the production of antibodies not only to a staphylococcus antigen, but also of antibodies reacting with an extract of homologous kidneys, myocardium and the skin. The presence in the pathogenic staphylococcus of an antigen affiliated to proteins of the skin and kidneys of rabbits and mice was shown by the method of cross sorption of antistaphylococcus and antiskin sera by a suspension of the staphylococcus or skin antigen with the use of the complement fixation test. Indirect hemagglutination and immunofluorescence. Such antigen was absent in nonpathogenic bacteria isolated from the skin extracts.
在兔子身上进行了实验；金黄色葡萄球菌疫苗的初次和二次接种通常不仅会产生针对金黄色葡萄球菌抗原的抗体，还会产生与同源肾脏、心肌和皮肤提取物发生反应的抗体。通过使用补体结合试验，用金黄色葡萄球菌或皮肤抗原的悬浮液对抗金黄色葡萄球菌血清和抗皮肤血清进行交叉吸附的方法，证明了致病性金黄色葡萄球菌中存在一种与兔子和小鼠皮肤及肾脏蛋白质相关的抗原。间接血凝和免疫荧光法。从皮肤提取物中分离出的非致病性细菌中不存在这种抗原。
