Lohmann Ingrid, McGinnis William
Department of Biology, 0349, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Curr Biol. 2002 Aug 6;12(15):R514-6. doi: 10.1016/s0960-9822(02)01025-4.
Recent studies provide compelling new evidence that Hox gene effects depend on fine-structure spatial and temporal information. Further, in a specific cell type, only one or a few downstream genes may mediate Hox morphogenetic functions. If this is generally true, it will have important implications for how Hox regulatory networks operate and evolve.