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Impact of ACE polymorphism on renal allograft function, blood pressure, and proteinuria under ACE inhibition.

作者信息

Suwelack Barbara, Kempkes-Koch M, Kobelt V, Hillebrand U, Matzkies F, Gerhardt U, Hohage H

机构信息

Department of Internal Medicine D, University of Muenster, Albert Schweitzer Strasse 33, D-48129 Münster, Germany.

出版信息

Transplant Proc. 2002 Aug;34(5):1763-6. doi: 10.1016/s0041-1345(02)03058-0.

DOI:10.1016/s0041-1345(02)03058-0
PMID:12176567
Abstract
摘要

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ACE polymorphism does not determine short-term renal response to ACE-inhibition in proteinuric patients.血管紧张素转换酶(ACE)基因多态性并不能决定蛋白尿患者对ACE抑制治疗的短期肾脏反应。
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Insertion/Deletion polymorphism of Angiotensin-converting enzyme as a risk factor for chronic allograft nephropathy.血管紧张素转换酶插入/缺失多态性作为慢性移植肾肾病的危险因素
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J Hypertens. 2007 Oct;25(10):2082-92. doi: 10.1097/HJH.0b013e3282b9720e.

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Does the Angiotensin-converting enzyme (ACE) gene insertion/deletion polymorphism modify the response to ACE inhibitor therapy?--A systematic review.血管紧张素转换酶(ACE)基因插入/缺失多态性是否会改变对ACE抑制剂治疗的反应?——一项系统评价。
Curr Control Trials Cardiovasc Med. 2005 Oct 24;6(1):16. doi: 10.1186/1468-6708-6-16.
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What is the impact of the ACE gene insertion/deletion (I/D) polymorphism on the clinical effectiveness and adverse events of ACE inhibitors?--Protocol of a systematic review.血管紧张素转换酶(ACE)基因插入/缺失(I/D)多态性对ACE抑制剂临床疗效及不良事件有何影响?——一项系统评价方案
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