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联合前后路手术治疗与I型Chiari畸形相关的基底凹陷症

Combined anterior and posterior approach for managing basilar invagination associated with type I Chiari malformation.

作者信息

Zileli Mehmet, Cagli Sedat

机构信息

Ege University Faculty of Medicine, Department of Neurosurgery, Bornova, Izmir, Turkey.

出版信息

J Spinal Disord Tech. 2002 Aug;15(4):284-9. doi: 10.1097/00024720-200208000-00004.

Abstract

Ventral brainstem compression is common in patients with basilar invagination associated with type I Chiari malformation. The aim of this study was to investigate the reliability of a combined one-session anterior-posterior surgical approach for these patients. Nine patients underwent transoral odontoidectomy, posterior foramen magnum decompression, occipitocervical fixation, and bone grafting. All but two patients had ventral and dorsal operations in one surgical sitting. One of these two individuals had previously undergone posterior decompressive surgery at another hospital, but his condition had deteriorated rapidly afterward. The mean follow-up time was 19 months (range, 14-30 months). There was no mortality and no significant morbidity in this series. All but one of the patients showed significant improvement in their symptoms. Chiari malformations have a surprisingly high association with basilar invagination, and patients may have symptoms in both conditions. If there is a marked anterior compression, anterior transoral and posterior decompression, fusion, and instrumentation is an optimal strategy for treating patients with basilar invagination associated with type I Chiari malformation.

摘要

腹侧脑干受压在伴有Ⅰ型Chiari畸形的基底凹陷患者中很常见。本研究的目的是探讨一种联合一期前后路手术方法治疗这些患者的可靠性。9例患者接受了经口齿状突切除术、枕大孔后减压术、枕颈固定术和植骨术。除2例患者外,其余患者均在一次手术中完成了腹侧和背侧手术。这2例患者中的1例曾在另一家医院接受过后路减压手术,但术后病情迅速恶化。平均随访时间为19个月(范围14 - 30个月)。本系列中无死亡病例,也无明显并发症。除1例患者外,所有患者的症状均有明显改善。Chiari畸形与基底凹陷的关联出奇地高,患者在这两种情况下都可能出现症状。如果存在明显的前路压迫,经口前路和后路减压、融合及内固定是治疗伴有Ⅰ型Chiari畸形的基底凹陷患者的最佳策略。

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