Singh R, Singh T P
Ann Endocrinol (Paris). 1975 Nov-Dec;36(6):309-16.
Hypothalamic extract has been found to contain certain factor(s) which triggers the release of prolactin from the pituitary gland. In assay recipients, hypothalamic extract injection was as effective as perphenazine-HCl treatment in triggering the release of prolactin from pituitary gland. Rise in prolactin concentration of serum and resultant decrease in pituitary prolactin level in response to hypothalamic extract administration suggests that hypothalamus in H. fossilis has prolactin releasing factor(s). This releasing effect of hypothalamus seems to be specific since cortical extract injections were ineffective in producing the similar response.
已发现下丘脑提取物含有某些因子，可触发垂体释放催乳素。在实验受体中，注射下丘脑提取物在触发垂体释放催乳素方面与盐酸奋乃静治疗效果相同。给予下丘脑提取物后，血清催乳素浓度升高，垂体催乳素水平随之下降，这表明化石蟾蜍的下丘脑具有催乳素释放因子。下丘脑的这种释放作用似乎具有特异性，因为注射皮质提取物未能产生类似反应。
