Szybiński Z, Huszno B, Rachtan J, Przybylik-Mazurek E, Buziak-Bereza M, Trofimiuk M
Katedry i Kliniki Endokrynologii, Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie.
Wiad Lek. 2001;54 Suppl 1:106-16.
The aim of the paper is to analyse the epidemiological situation of thyroid cancer in Cracow region from 1986 to 1999 and to review regional thyroid cancer registers in Poland (including 43.7% of the Polish population) in 1999. The standardized register was based upon assumptions: 100% of histopathological verification according to ICD-10, the register ascertainment in at least 80%, the demographic area not smaller than 100,000 inhabitants, the incidence rate (IR) calculated as the newly diagnosed cases number per 100,000 inhabitants in a calendar year. Since 1990 a statistically significant rise of the thyroid cancer incidence affecting mainly women > 40 years of age have been observed. From 1998-1999 the cancer morbidity was reduced. Within the last 5 years in the Cracow area the follicular carcinoma incidence has decreased significantly, which has been associated with effective iodine prophylaxis. The highest incidence values have been observed in Cracow and Olsztyn, showing a territorial relationship with the highest thyroid irradiation doses after Chernobyl accident. The mean IR value has been 3.86 (1.48 men, 6.08 women), which corresponds to about 1500 newly diagnosed cases in Poland in 1999. The follicular to papillary carcinoma ratio has been 5.32. The major etiological factors have been iodine deficiency and ionising radiation. The present data have indicated that iodine prophylaxis should be continued and that the population should be protected against ionising radiation.
本文旨在分析1986年至1999年克拉科夫地区甲状腺癌的流行病学情况,并回顾1999年波兰地区甲状腺癌登记情况(涵盖43.7%的波兰人口)。标准化登记基于以下假设:根据国际疾病分类第十版(ICD - 10)进行100%的组织病理学验证,登记确诊率至少为80%,人口统计区域居民不少于10万,发病率(IR)按日历年每10万居民中新确诊病例数计算。自1990年以来,观察到甲状腺癌发病率有统计学意义的上升,主要影响40岁以上女性。1998 - 1999年癌症发病率有所下降。在过去5年中,克拉科夫地区滤泡状癌发病率显著下降,这与有效的碘预防措施有关。在克拉科夫和奥尔什丁观察到最高发病率值,显示出与切尔诺贝利事故后最高甲状腺辐射剂量的地域关系。平均发病率值为3.86(男性1.48,女性6.08),这相当于1999年波兰约1500例新确诊病例。滤泡状癌与乳头状癌的比例为5.32。主要病因是碘缺乏和电离辐射。目前的数据表明应继续进行碘预防,并且应保护人群免受电离辐射。