Hauser S L, DeLong G R, Rosman N P
Brain. 1975 Dec;98(4):667-88. doi: 10.1093/brain/98.4.667.
Pneumoencephalographic findings are described in a group of 18 children who presented to us with a history of retarded language development and autistic behaviour disturbances. None had specific diagnosable neurological diseases nor gross motor disorders. PEG findings included, most prominently, pathological enlargement of the left temporal horn in 15 cases; some cases showed enlargement of both temporal horns or mild variable enlargement of the lateral ventricles, especially the left. Comparisons between infantile autism and recognized patterns of temporal lobe disease (especially Korsakoff syndrome and Kluver-Bucy syndrome) are drawn. We have suggested that medial temporal lobe dysfunction may be a major factor in the pathogenesis of the syndrome of infantile autism.
本文描述了一组18名儿童的气脑造影检查结果，这些儿童均有语言发育迟缓及自闭症行为障碍病史。他们均无特定可诊断的神经疾病，也无明显的运动障碍。气脑造影检查结果最显著的是，15例患儿左侧颞角病理性增大；部分病例显示双侧颞角增大或侧脑室轻度不同程度增大，尤其是左侧。文中对婴儿自闭症与公认的颞叶疾病模式（特别是科萨科夫综合征和克卢弗-布西综合征）进行了比较。我们认为颞叶内侧功能障碍可能是婴儿自闭症综合征发病机制中的一个主要因素。
