Requena Luis, Kutzner Heinz, Mentzel Thomas
Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.
J Am Acad Dermatol. 2002 Sep;47(3):371-6. doi: 10.1067/mjd.2002.122737.
In recent years, many new cutaneous vascular proliferations have been described. This is partly due to the current epidemic of AIDS, which has forced dermatopathologists to establish the diagnosis of the earliest patch-stage lesions of AIDS-related Kaposi's sarcoma and some of the recently described cutaneous vascular proliferations that may histopathologically mimic lesions of early Kaposi's sarcoma.
This article reports the clinical, histopathologic, and immunohistochemical findings in 6 cases of a clinicopathologic variant of cutaneous hemangioma, which we have named acquired elastotic hemangioma.
Six cases of acquired elastotic hemangioma were studied from clinical, histopathologic, and immunohistochemical standpoints. The histopathologic differential diagnosis with other similar cutaneous vascular proliferations is discussed.
Acquired elastotic hemangioma appears on the sun-damaged skin of the dorsal aspect of the forearms or on the lateral aspects of the neck of middle-aged or elderly women. Clinically, lesions present as solitary erythematous plaques with variable morphology and in only some cases have a clearly angiomatous appearance. On histopathologic examination, acquired elastotic hemangioma is characterized by a band-like proliferation of capillary blood vessels involving the superficial dermis and arranged horizontally parallel to the epidermis.
Acquired elastotic hemangioma is a distinctive clinicopathologic variant of hemangioma that should be differentiated from other cutaneous vascular proliferations. On histopathologic examination, it is characterized by capillary proliferation involving the dermis.
近年来,已描述了许多新的皮肤血管增生性病变。部分原因是当前艾滋病的流行,这迫使皮肤病理学家对艾滋病相关卡波西肉瘤的最早斑块期病变以及一些最近描述的在组织病理学上可能模仿早期卡波西肉瘤病变的皮肤血管增生性病变进行诊断。
本文报告6例皮肤血管瘤临床病理变异型的临床、组织病理学和免疫组化结果,我们将其命名为获得性弹性化血管瘤。
从临床、组织病理学和免疫组化角度研究6例获得性弹性化血管瘤。讨论了与其他类似皮肤血管增生性病变的组织病理学鉴别诊断。
获得性弹性化血管瘤出现在中年或老年女性前臂背侧受阳光损伤的皮肤或颈部侧面。临床上,病变表现为形态各异的孤立性红斑斑块,仅在某些情况下具有明显的血管瘤外观。组织病理学检查显示,获得性弹性化血管瘤的特征是毛细血管呈带状增生,累及浅表真皮,并与表皮水平平行排列。
获得性弹性化血管瘤是一种独特的血管瘤临床病理变异型,应与其他皮肤血管增生性病变相鉴别。组织病理学检查显示,其特征为累及真皮的毛细血管增生。