Zaenglein Andrea L, Heintz Patrick, Kamino Hideko, Zisblatt Martin, Orlow Seth J
Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York 10016, USA.
J Am Acad Dermatol. 2002 Sep;47(3):441-4. doi: 10.1067/mjd.2002.117226.
The differentiation between atypical variants of Spitz nevus and melanoma is often difficult given the many clinical and histopathologic similarities between the two. We report a case of an infant with a congenital scalp lesion exhibiting clinical features of melanoma, including variegation and regression of pigmentation and a rapidly changing appearance. Histologic examination of the excised lesion revealed a benign congenital Spitz nevus. This case emphasizes the need for clinical and histologic correlation in determining the benign or malignant nature of atypical pigmented lesions in infants.
鉴于Spitz痣的非典型变体与黑色素瘤在临床和组织病理学上存在诸多相似之处，二者的鉴别往往颇具难度。我们报告了一例患有先天性头皮病变的婴儿病例，该病变呈现出黑色素瘤的临床特征，包括色素沉着的斑驳和消退以及外观迅速变化。对切除病变的组织学检查显示为良性先天性Spitz痣。该病例强调了在确定婴儿非典型色素沉着病变的良性或恶性性质时临床与组织学相互关联的必要性。
