Brunetti Davide, Tamaro Paolo, Stanta Giorgio
Registro dei tumori della Provincia di Trieste, Ospedale S. Santorio, via Bonomea 265, 34136 Trieste.
Epidemiol Prev. 2002 May-Jun;26(3):130-9.
We analysed incidence, survival and mortality from cancer among people aged 15-24 years resident in the province of Trieste, Italy, during 1972-1993, and evaluated the quality of the local diagnostic facilities and of the care provided by local hospital departments. We compared the results with those previously published on childhood cancer. We recorded 118 new cases of cancer (96% microscopically verified) corresponding to a rate, age-standardized to the world population, of 162.3 (standard error SE = 15.0) per million person-years. The diagnostic group with the highest rate was that of carcinomas (54.5; SE = 8.7; 40 cases). The diagnosis was reached at hospitals in the province of Trieste for 107 cases, with a median time of nine days (25th-75th percentile = 5-23) between admission and diagnosis. Among patients with leukaemias, lymphomas and brain tumours, this interval was longer than in children affected by the same neoplasms. One girl with cancer of the uterine cervix refused all treatment. The therapy of the other 117 cases were co-ordinated by 29 different departments of hospitals located in Trieste for 86 cases, in other Italian hospitals for 26 cases and in European hospitals for five cases. On the other hand, out of 123 childhood cancers 107 were co-ordinated by three departments in Trieste, seven by other Italian hospitals and nine by foreign hospitals. The 10-year survival probabilities of children with acute lymphoblastic leukaemia and non-Hodgkin lymphomas were higher than those of patients aged 15-24 years: 66.7% (SE = 9.1) vs 14.3% (SE = 13.2) and 77.8% (SE = 13.9) vs 40.0% (SE = 21.9), respectively.
我们分析了1972年至1993年期间居住在意大利的里雅斯特省15至24岁人群的癌症发病率、生存率和死亡率，并评估了当地诊断设施的质量以及当地医院科室提供的护理质量。我们将结果与之前发表的儿童癌症研究结果进行了比较。我们记录了118例新癌症病例（96%经显微镜确诊），按世界人口年龄标准化后的发病率为每百万人年162.3例（标准误差SE = 15.0）。发病率最高的诊断组是癌（54.5；SE = 8.7；40例）。107例病例在的里雅斯特省的医院确诊，入院至确诊的中位时间为9天（第25至75百分位数 = 5至23天）。在白血病、淋巴瘤和脑肿瘤患者中，这一间隔时间比患相同肿瘤的儿童更长。一名子宫颈癌女孩拒绝了所有治疗。其他117例病例的治疗由的里雅斯特的29个不同医院科室协调，其中86例在当地，26例在意大利其他医院，5例在欧洲医院。另一方面，在123例儿童癌症病例中，107例由的里雅斯特的三个科室协调，7例由意大利其他医院协调，9例由外国医院协调。急性淋巴细胞白血病和非霍奇金淋巴瘤儿童的10年生存率高于15至24岁患者：分别为66.7%（SE = 9.1）对14.3%（SE = 13.2）和77.8%（SE = 13.9）对40.0%（SE = 21.9）。
