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[细小病毒B19感染所致家族性暂时性红细胞再生障碍]

[Familial transient red cell aplasia from parvovirus B-19 infection].

作者信息

Salvini F, Tonella M, Carpani G, Scaglioni S, Zuccotti G V

机构信息

Clinica Pediatrica dell'Università di Milano, Ospedale San Paolo, Via A. di Rudinì, 8, 20142 Milano.

出版信息

Pediatr Med Chir. 2002 Jul-Aug;24(4):306-7.

Abstract

In our Paediatric Clinic we observed a case of transient aplastic crisis caused by Parvovirus B19 in a child and his mother, both affected by spherocytic haemolytic anemia. Anti-Parvovirus IgM antibody titre and viral search by PCR were positive. Anemia was treated with transfusion of concentrated red blood cells. In case of a family onset of hyperacute anemia it is necessary to consider a bone marrow aplastic crisis of the red series, induced by Parvovirus B19, especially if there is notice of an ongoing outbreak of erythema infectiosum.

摘要

在我们的儿科诊所,我们观察到一名儿童及其母亲因细小病毒B19引发了短暂再生障碍危象,他们两人均患有球形红细胞溶血性贫血。抗细小病毒IgM抗体滴度以及通过聚合酶链反应进行的病毒检测均呈阳性。贫血通过输注浓缩红细胞进行治疗。如果出现超急性贫血的家族性发病情况,有必要考虑由细小病毒B19诱发的红系骨髓再生障碍危象,尤其是在有传染性红斑正在爆发的报告时。

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