Patiroğlu Türkan, Kürşad Aydin, Kurtoğlu Selim, Poyrazoğlu Hakan
Department of Pediatrics, Erciyes University Medical Faculty, Kayseri, Turkey.
J Pediatr Endocrinol Metab. 2002 Jul-Aug;15(7):1035-8.
We evaluated the clinical and immunological manifestations of 14 children with IgA deficiency. Four of the patients were asymptomatic, and ten were symptomatic, with recurrent sinopulmonary infections, allergic disease, recurrent intestinal giardiasis or celiac disease. Growth retardation was the second important feature in our patients. One of the seven patients with growth retardation had partial growth hormone deficiency. The levels of serum IgG and IgM were high in five and three patients, respectively. Cellular immunity was normal.
我们评估了14例IgA缺乏症患儿的临床和免疫表现。4例患者无症状，10例有症状，表现为反复的鼻窦肺部感染、过敏性疾病、反复的肠道贾第虫病或乳糜泻。生长发育迟缓是我们患者的第二个重要特征。7例生长发育迟缓的患者中有1例存在部分生长激素缺乏。5例和3例患者的血清IgG和IgM水平分别升高。细胞免疫正常。
