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[不孕症的细胞遗传学研究]

[Cytogenetic studies in infertility].

作者信息

Körner H

出版信息

Zentralbl Gynakol. 1975;97(8):467-74.

PMID:1220458
Abstract

10 TO 15% of all married couples are undesired childless. New investigations show the tendency of a wider increase. Infertility is a possibility caused chromosomaly. In married couples carriers of balanced translocations causing repeated spontaneous abortions in a rate of ten times more than in the normal population. Every 50 married partner is a carrier. Chromosomal cause of infertility should be excluded before an operative therapy is planed and gives a base for genetic counseling.

摘要

所有已婚夫妇中有10%至15%是不想要孩子但没有孩子。新的调查显示有进一步增加的趋势。不孕不育是一种由染色体异常导致的可能性。在已婚夫妇中,平衡易位携带者导致反复自然流产的发生率比正常人群高出十倍。每50个已婚伴侣中就有一个是携带者。在计划进行手术治疗之前,应排除不孕不育的染色体原因,并为遗传咨询提供依据。

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