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[葡萄膜炎合并脑脊膜炎1例(作者译)]

[A case of uveitis and meningo-myelitis (author's transl)].

作者信息

Schoenen J, Delwaide P J

出版信息

Acta Neurol Belg. 1975;75(6):267-78.

PMID:1220522
Abstract

The authors describe a patient, suffering from recurring uveitis, buccal aphthous ulcers and meningo-myelitis. The diagnosis of Behcet's disease accounts for the whole clinical picture and has been confirmed by a cutaneous hypersensitivity to scratching. The authors stress the similarity between the neurological aspects of Behcet's disease and multiple sclerosis not only on the clinical side but also concerning the CSF composition (lympho-mono-plasmatocytic meningogram, increase and fractionation of gammaglobulins). The authors present a critical review of the evidence in favour of a viral aetiology. They put forward the clinical and experimental data in favour of an auto-immune aetiopathogeny. Treatment with corticosteroids associated with immunosuppressive drugs proved beneficial.

摘要

作者描述了一名患有复发性葡萄膜炎、口腔阿弗他溃疡和脑脊膜炎的患者。白塞病的诊断符合整个临床症状,并通过皮肤划痕过敏反应得到证实。作者强调,白塞病的神经学方面与多发性硬化症不仅在临床方面相似,而且在脑脊液成分方面(淋巴细胞-单核细胞-浆细胞性脑脊膜炎造影、γ球蛋白增加和分离)也相似。作者对支持病毒病因的证据进行了批判性综述。他们提出了支持自身免疫性发病机制的临床和实验数据。使用皮质类固醇联合免疫抑制药物治疗证明是有益的。

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