Choe Y B, Rim J H, Youn Jai-Il
Department of Dermatology, University Hospital, Seoul National University College of Medicine, 28-Yongon-dong, Chongno-gu, Seoul 110-744, Korea.
Photodermatol Photoimmunol Photomed. 2002 Jun;18(3):127-30. doi: 10.1034/j.1600-0781.2002.00730.x.
BACKGROUND/PURPOSE: Narrow-band (TL-01) UVB lamps are being increasingly used for phototherapy of psoriasis and other dermatoses, for their excellent effect compared with broad-band UVB sources. Many patients receiving phototherapy have complained about the tanning effect of ultraviolet radiation especially in dark-skinned ones. So we wished to know the degree of pigmentation induced by phototherapy during narrow-band UVB treatment.
A total of 20 psoriasis patients receiving narrow-band UVB phototherapy were included in this study. A Minolta spectrophotometer CM-2002 was used to measure pigmentation. All patients were evaluated for skin color every seventh day for 7 weeks. The L* value (luminance) gives information about the relative lightness ranging from total black to pure white. The a* value represents the balance between red and green, and the b* value between yellow and blue.
The L* values which indicate luminance decreased continuously until the 5th week, when maximum tanning was obtained. Afterwards minimal change was observed until the 7th week. The change of a* and b* values also showed the pattern that was compatible with the above results. The mean individual typology angle of our subjects was 41.9 degrees, which indicated they fell into "light" group of constitutional skin color category.
From this study, we found that pigmentation induced by narrow-band UVB phototherapy increased continuously until the 5th week and then did not progress. Our results provide standard data of skin pigmentation during narrow-band UVB phototherapy in Korean brown skin.
背景/目的:与宽带UVB光源相比,窄谱(TL-01)UVB灯因其卓越的疗效,正越来越多地用于银屑病和其他皮肤病的光疗。许多接受光疗的患者抱怨紫外线辐射的晒黑效果,尤其是深色皮肤的患者。因此,我们希望了解窄谱UVB治疗期间光疗引起的色素沉着程度。
本研究共纳入20例接受窄谱UVB光疗的银屑病患者。使用美能达分光光度计CM-2002测量色素沉着。所有患者在7周内每隔7天评估一次皮肤颜色。L值(亮度)提供了从全黑到纯白的相对亮度信息。a值代表红色和绿色之间的平衡,b*值代表黄色和蓝色之间的平衡。
表示亮度的L值持续下降,直到第5周达到最大晒黑程度。此后,直到第7周观察到最小变化。a和b*值的变化也显示出与上述结果相符的模式。我们受试者的平均个体类型角度为41.9度,表明他们属于体质皮肤颜色类别的“浅色”组。
通过本研究,我们发现窄谱UVB光疗引起的色素沉着在第5周前持续增加,之后不再进展。我们的结果提供了韩国棕色皮肤窄谱UVB光疗期间皮肤色素沉着的标准数据。