腹股沟疝开放补片修补术与非补片修补术：基于个体患者数据的随机试验荟萃分析[校正后]

Open mesh versus non-mesh repair of groin hernia: meta-analysis of randomised trials based on individual patient data [corrected].

作者信息

Grant A M

机构信息

Health Services Research Unit, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, UK.

出版信息

Hernia. 2002 Sep;6(3):130-6. doi: 10.1007/s10029-002-0073-1. Epub 2002 Jul 26.

DOI:10.1007/s10029-002-0073-1

PMID:12209302

Abstract

BACKGROUND

The EU Hernia Trialists Collaboration was established to provide reliable evaluation of newer methods of groin hernia repair. It involved 70 investigators in 20 countries.

MATERIALS AND METHODS

Twenty eligible trials (5016 participants) of open mesh vs. non-mesh groin hernia repair were identified. Meta-analysis was performed using raw individual patient data where possible.

RESULTS

Fewer hernia recurrences were reported after mesh repair. There were no clear differences between mesh and non-mesh groups in complications. Overall, those in the mesh groups had a shorter hospital stay, quicker return to usual activities and less frequent persisting pain, but individual trial results varied.

CONCLUSIONS

The review provides strong evidence that open mesh repair is associated with a reduction in the risk of recurrence of between 50% and 75%. There is also some evidence of quicker recovery and of lower rates of persisting pain following open mesh repair.

摘要