Grant A M
Health Services Research Unit, Foresterhill, Aberdeen, UK.
Hernia. 2002 Mar;6(1):2-10. doi: 10.1007/s10029-002-0050-8.
The EU Hernia Trialists Collaboration was established to provide reliable evaluation of newer methods of groin hernia repair. It involved 70 investigators in 20 countries. The aim was to perform systematic reviews and enhance the value of individual studies by reanalysis of data from randomised controlled trials in meta-analyses. Forty-one eligible trials of laparoscopic versus open groin hernia repair were identified involving 7161 participants (with individual patient data available for 4165). Meta-analysis was performed, using individual patient data where possible. Operation times for laparoscopic repair were longer and there was a higher risk of rare serious complications. Return to usual activities was faster, and there was less persisting pain and numbness. Hernia recurrence was less common than after open non-mesh repair but not different to open mesh methods. The review showed that laparoscopic repair takes longer and has more serious complications, but recovery is quicker with less persisting pain. Reduced hernia recurrence was related to the use of mesh rather than the method of mesh placement.
欧盟疝试验协作组的成立旨在对腹股沟疝修补的新方法进行可靠评估。它涉及20个国家的70名研究人员。其目的是进行系统评价，并通过在荟萃分析中重新分析随机对照试验的数据来提高单个研究的价值。共确定了41项比较腹腔镜与开放腹股沟疝修补术的合格试验，涉及7161名参与者（其中4165名有个体患者数据）。尽可能使用个体患者数据进行荟萃分析。腹腔镜修补术的手术时间更长，罕见严重并发症的风险更高。恢复日常活动更快，持续疼痛和麻木更少。疝复发比开放无网片修补术后少见，但与开放网片修补方法无差异。该综述表明，腹腔镜修补术耗时更长，并发症更严重，但恢复更快，持续疼痛更少。疝复发减少与使用网片有关，而非网片放置方法。
