Jensen-Fangel Søren, Pedersen Court, Larsen Carsten Schade, Tauris Palle, Møller Axel, Obel Niels
Infektionsmedicinsk afdeling Q, Skejby Sygehus, Arhus Universitetshospital, DK-8200 Arhus N.
Ugeskr Laeger. 2002 Aug 19;164(34):3964-7.
The course of HIV infection has changed since the introduction of highly active anti-retroviral treatment.
We present demographic data from an observational database on HIV and AIDS in the Western part of Denmark, a region representing 2,935,156 individuals, or 55.1% of the population in Denmark (1 January 2000). Five centres in the region treat HIV positive adults; all patients attached to these centres since 1995 are included. Altogether 749 adult HIV-infected individuals were enrolled as of 31 December 1999. Estimates of the prevalence and incidence of HIV infection in the area were 25.8/100,000 and 2.6/100,000 respectively, which are lower than the average for the country.
The number of newly diagnosed HIV-infected patients remained constant in the period 1995-1999 with an average of 62 diagnoses per year. The number of HIV-related deaths declined from 43 in 1995 to 15 in 1999.
There seems to be a shift in the HIV epidemic over the last few years, with a higher proportion of newly diagnosed HIV-patients who have contracted the infection through heterosexual contact, and a higher proportion who are immigrants from less developed countries.
自从引入高效抗逆转录病毒治疗后,HIV感染的病程已发生改变。
我们展示了丹麦西部一个关于HIV和艾滋病的观察性数据库中的人口统计学数据,该地区代表2935156人,占丹麦人口的55.1%(2000年1月1日)。该地区的五个中心治疗HIV阳性成年人;纳入了自1995年以来隶属于这些中心的所有患者。截至1999年12月31日,共纳入749名成年HIV感染者。该地区HIV感染的患病率和发病率估计分别为25.8/10万和2.6/10万,低于该国平均水平。
1995 - 1999年期间,新诊断的HIV感染患者数量保持稳定,平均每年62例诊断。HIV相关死亡人数从1995年的43例降至1999年的15例。
在过去几年中,HIV流行情况似乎出现了转变,新诊断的HIV患者中通过异性接触感染的比例更高,且来自欠发达国家的移民比例更高。