Abbondanza A, Cessi C
Arch Sci Biol (Bologna). 1978 Jan-Dec;62(1-4):77-82.
The concentrations of gamma-amino-n-butyric acid in brains of rats intoxicated with half intraperitoneal LD50 ethanol were determined at various times and found increased at early times (10 min) and decreased later (1 to 3 hours). The concentration tended to be restored to normal values upon administration of n-dipropylacetate (400 mg/kg) or L-glutamine (340 mg/kg). The treatment with both substances showed a positive interaction with an overall positive effect greater than the sum of each.
测定了经腹腔注射半数致死量乙醇中毒的大鼠在不同时间大脑中γ-氨基丁酸的浓度，发现在早期（10分钟）升高，后期（1至3小时）降低。给予二丙基乙酸（400毫克/千克）或L-谷氨酰胺（340毫克/千克）后，浓度趋于恢复到正常值。两种物质的治疗显示出正相互作用，总体积极效果大于每种物质单独作用之和。
