Liu L, Yue S, Jiang H, Lu T
College of Stomatology, West China University of Medical Sciences.
Hua Xi Kou Qiang Yi Xue Za Zhi. 1998 May;16(2):103-4, 113.
The rates of demineralization of 5 organic acids (mathanoic acid, formic acid, propionic acid, Lactic acid, acetic acid, mixed acid) to the bovine enamel were tested and analysed with the self-made calcium ionselective microelectrodes(Ca(2+)-ISME) basing on a neutral carriers of ETH1001. The results showed; 1. The difference between the rates of demineralization of formic acid and lactic acid, formic acid and propionic acid, formic acid and acetic acid, acetic acid and mixed acid, acetic acid and lactic acid, propionic acid and mixed acid, propionic acid and lactic acid, lactic acid and mixed acid were of great significance (P < 0.01); 2. The rates of demineralization of acetic and mixed acid decreased with time, due to saturation of the solution during demineralization; 3. Ca(2+)-ISME was of the advantages of simplicity, rapidity, sensitivity and accuracy. The results suggest that the cariogenic potential is related to different acid products of different cariogenic bacteria, and the degree of mineral saturation within solution affects the rate of demineralization.
使用基于ETH1001中性载体自制的钙离子选择性微电极（Ca(2+)-ISME），对5种有机酸（甲酸、乙酸、丙酸、乳酸、混合酸）对牛牙釉质的脱矿速率进行了测试和分析。结果表明：1. 甲酸与乳酸、甲酸与丙酸、甲酸与乙酸、乙酸与混合酸、乙酸与乳酸、丙酸与混合酸、丙酸与乳酸、乳酸与混合酸的脱矿速率差异具有极显著意义（P < 0.01）；2. 乙酸和混合酸的脱矿速率随时间下降，这是由于脱矿过程中溶液达到饱和；3. Ca(2+)-ISME具有简单、快速、灵敏和准确的优点。结果表明，致龋潜力与不同致龋菌产生的不同酸性产物有关，溶液中的矿物质饱和度会影响脱矿速率。
