Different types of DNA synthesis and their importance in cancer growth and therapy.

Three main types of DNA replication has been recognized: spontaneous, stimulated and induced synthesis. The spontaneous synthesis requires, in addition to the building blocks assembled by a series of enzymes, a preexisting DNA chain which plays both as template and primer. Such pattern, operatively completed during S phase of the cycle, is strictly dependent on the structural integrity of DNA molecule and on the energy level which provokes the signal of initiation.