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成人过敏性紫癜伴肾小球肾炎和阵发性夜间血红蛋白尿:一种罕见的关联。

Adult Henoch-Schönlein purpura with glomerulonephritis and paroxysmal nocturnal haemoglobinuria: an uncommon association.

作者信息

Cozzi F, Botsios C, Ostuni P, Sfriso P, Piva E, Marson P, Punzi L, Todesco S

机构信息

University of Padua, Padua, Italy.

出版信息

Clin Rheumatol. 2002 Sep;21(5):408-10. doi: 10.1007/s100670200109.

Abstract

Henoch-Schönlein purpura (HSP) is considered to be a small blood vessel systemic vasculitis. Numerous microorganisms have been implicated in triggering HSP. We describe an unusual case of HSP with glomerulonephritis and renal failure requiring haemodialysis in a young adult man who subsequently developed paroxysmal nocturnal haemoglobinuria (PNH) with several haemolytic episodes. Bacterial infections, especially those of the respiratory and urinary tract, might trigger both the diseases.

摘要

过敏性紫癜(HSP)被认为是一种小血管系统性血管炎。许多微生物被认为与HSP的触发有关。我们描述了一例不寻常的HSP病例,该患者为一名年轻成年男性,患有肾小球肾炎和肾衰竭,需要进行血液透析,随后又出现了阵发性夜间血红蛋白尿(PNH)并伴有多次溶血发作。细菌感染,尤其是呼吸道和泌尿道感染,可能会引发这两种疾病。

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