Suppr超能文献

斯里兰卡北部疟疾及时有效治疗的障碍。

Barriers to prompt and effective treatment of malaria in northern Sri Lanka.

作者信息

Reilley B, Abeyasinghe R, Pakianathar M Vincent

机构信息

Medecins sans Frontieres, Colombo, Sri Lanka.

出版信息

Trop Med Int Health. 2002 Sep;7(9):744-9. doi: 10.1046/j.1365-3156.2002.00919.x.

Abstract

BACKGROUND

For the past 18 years, northern Sri Lanka has been affected by armed ethnic conflict. This has had a heavy impact on displacement of civilians, health delivery services, number of health professionals in the area and infrastructure. The north of Sri Lanka has a severe malaria burden, with less than 5% of the national population suffering 34% of reported cases. Health care providers investigated treatment-seeking behaviour and levels of treatment failure believed to be the result of lack of adherence to treatment.

METHODS

Pre- and post-treatment interviews with patients seeking treatment in the outpatient department (OPD) and focus groups.

RESULTS

A total of 271 persons completed interviews: 54.4% sought treatment within 2 days of the onset of symptoms, and 91.9% self-treated with drugs with prior to seeking treatment, mainly with paracetamol. Self-treatment was associated with delaying treatment (RR 3.55, CI 1.23-10.24, P=0.002). In post-treatment interviews, self-reported default was 26.1%. The main reasons for not taking the entire regimen were side-effects (57.6%) and disappearance of symptoms (16.7%). Focus groups indicated some lack of confidence in chloroquine treatment and prophylaxis, and scant enthusiasm for prevention methods.

CONCLUSIONS

A number of factors contribute to a lack of access and a lower quality of care for malaria: lack of medical staff and facilities because of the fighting; lack of confidence in treatment, and perception of malaria as a routine illness. Prevention efforts need to take into account certain beliefs and practices to be successful.

摘要

背景

在过去18年里,斯里兰卡北部一直受到武装民族冲突的影响。这对平民流离失所、医疗服务、该地区卫生专业人员数量和基础设施都产生了重大影响。斯里兰卡北部疟疾负担沉重,全国不到5%的人口却承受了34%的报告病例。医疗服务提供者调查了寻求治疗的行为以及被认为是由于不坚持治疗导致的治疗失败率。

方法

对在门诊部(OPD)寻求治疗的患者进行治疗前和治疗后的访谈以及焦点小组访谈。

结果

共有271人完成了访谈:54.4%的人在症状出现后2天内寻求治疗,91.9%的人在寻求治疗前自行用药,主要是对乙酰氨基酚。自行治疗与延迟治疗相关(相对危险度3.55,可信区间1.23 - 10.24,P = 0.002)。在治疗后的访谈中,自我报告的未完成治疗率为26.1%。未完成整个疗程的主要原因是副作用(57.6%)和症状消失(16.7%)。焦点小组表明对氯喹治疗和预防缺乏信心,对预防方法也缺乏热情。

结论

多种因素导致疟疾的治疗可及性差和治疗质量低:由于冲突导致医务人员和设施短缺;对治疗缺乏信心,以及将疟疾视为常见疾病。预防工作要取得成功需要考虑某些观念和做法。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验