Tiutiulkova N I, Gorancheva Iu I
Eksp Med Morfol. 1975;14(4):187-9.
The authors examined the excretion of dopamine, noradrenaline, drenaline, vanylalmond acid and 5-hydroxyindolacetic acid in urine of healthy volunteers, treated with the original Bulgarian preparation Adepren for a period of ten days. There was an increase of the excretion of dopamine and adrenaline, but a tendency to a reduction of noradrenaline and vanylalmond acid. There were no changes in the excretion of 5-hydroxyindolacetic acid. The authors interpreted the obtained results most probably of MAO-inhibiting effect of the preparation.
作者检测了健康志愿者尿液中多巴胺、去甲肾上腺素、肾上腺素、香草扁桃酸和5-羟吲哚乙酸的排泄情况,这些志愿者用保加利亚原装制剂阿得普伦治疗了十天。多巴胺和肾上腺素的排泄增加,但去甲肾上腺素和香草扁桃酸有减少的趋势。5-羟吲哚乙酸的排泄没有变化。作者认为所获得的结果很可能是该制剂的单胺氧化酶抑制作用所致。