Seftel Allen D, Strohl Kingman P, Loye Tracy L, Bayard Dominique, Kress Jessica, Netzer Nikolaus C
Department of Urology, Cleveland VA Medical Center, University Hospitals of Cleveland, Case Western Reserve University, Ohio 44106, USA.
Sleep. 2002 Sep 15;25(6):643-7.
Sleep apnea often is associated with impotence and/or erectile dysfunction (ED). The purpose of this study was to test whether a presentation for ED confers a pretest probability for obstructive sleep apnea hypopnea syndrome (OSAHS).
A self-report survey for sleep complaints was conducted in consecutive male patients (>16 years of age) presenting to a urologic practice site.
The survey was provided to new and follow-up out-patients over a 2 month period of time. Other information collected included the presenting complaint, the clinical diagnosis for ED, and history of preexisting medical conditions.
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285 males [91% of the sample: 50 years old (range 16-82) and body mass index, 27.3 (range 16.8-52.5)] completed the survey. 181 (63%) had complaints of ED; of those, 76% had a final diagnosis of organic and 8.2%, psychogenic or both psychogenic and organic ED. Of all respondents, 35.4% reported persistent snoring, 14% reported persistent waketime sleepiness or fatigue, and 26.8% were at "high risk" (Netzer et al., 1999) for OSAHS. Some were high risk for insomnia (13.6%) and restless legs syndrome or for narcolepsy (2% each). There was a correlation between those with ED complaints (p<0.014) or those with a final diagnosis of organic ED (p<0.029) and snoring. In a logistic model that included age, snoring, and preexisting conditions, only age, depression, and history of hypercholesterolemia, were found to vary significantly among those with and without ED.
Urology patients will report a variety of sleep problems, but neither persistent snoring nor suspected OSAHS is correlated uniquely to ED.
睡眠呼吸暂停常与阳痿和/或勃起功能障碍(ED)相关。本研究的目的是测试因ED就诊是否会赋予阻塞性睡眠呼吸暂停低通气综合征(OSAHS)一个预检概率。
对在泌尿外科就诊的连续男性患者(年龄>16岁)进行了一项关于睡眠问题的自我报告调查。
在2个月的时间内,对新门诊患者和随访门诊患者进行了该调查。收集的其他信息包括就诊主诉、ED的临床诊断以及既往病史。
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285名男性[占样本的91%:年龄50岁(范围16 - 82岁),体重指数27.3(范围16.8 - 52.5)]完成了调查。181名(63%)有ED主诉;其中,76%最终诊断为器质性ED,8.2%为心因性或心因性与器质性混合性ED。在所有受访者中,35.4%报告有持续性打鼾,14%报告有持续性睡醒时困倦或疲劳,26.8%处于OSAHS的“高风险”(Netzer等人,1999年)。有些人存在失眠高风险(13.6%)、不安腿综合征或发作性睡病高风险(各2%)。有ED主诉者(p<0.014)或最终诊断为器质性ED者(p<0.029)与打鼾之间存在相关性。在一个包含年龄、打鼾和既往疾病的逻辑模型中,仅发现年龄、抑郁和高胆固醇血症病史在有ED和无ED者之间有显著差异。
泌尿外科患者会报告多种睡眠问题,但持续性打鼾或疑似OSAHS均未与ED有独特关联。