Campos-Juanatey Felix, Fernandez-Barriales Marcos, Gonzalez Monica, Portillo-Martin Jose A
Urology Department, Marques de Valdecilla University Hospital, Santander, 39008, Spain.
Institute of Investigation Marques de Valdecilla, Santander, 39011, Spain.
Asian J Androl. 2017 May-Jun;19(3):303-310. doi: 10.4103/1008-682X.170440.
Erectile dysfunction (ED) is considered a condition with a broad range of etiologies. Obstructive sleep apnea (OSA) syndrome is one of the lesser studied risk factors for ED. We intend to summarize the current evidence on the relationship between OSA and sexual impairment, focusing on the results in terms of erectile function of the different therapies offered to OSA patients. A systematic review was conducted, selecting articles related to the physiology of OSA and ED, and to the treatments of OSA syndrome and their reported outcomes in erectile and sexual function. Higher prevalences of ED in the OSA groups have been published. However, whether this effect on the erectile function occurs in the entire range of OSA severities remains unclear. Several hypotheses were proposed to explain the physiology of this association. Continuous Positive Airway Pressure as a treatment for OSA patients with ED has achieved a significative improvement in the sexual parameters in most of the studies. Phosphodiesterase type 5 inhibitors (iPDE5) on demand are useful as a treatment for ED in this subgroup of patients, with high satisfaction rates. The surgical treatment for the OSA evidenced benefits over the erectile function, and the effect on the sexual satisfaction of the therapy using Mandibular Advancement Devices is still undefined.
勃起功能障碍（ED）被认为是一种病因广泛的病症。阻塞性睡眠呼吸暂停（OSA）综合征是ED研究较少的危险因素之一。我们旨在总结当前关于OSA与性功能障碍之间关系的证据，重点关注针对OSA患者提供的不同治疗方法在勃起功能方面的结果。我们进行了一项系统综述，筛选了与OSA和ED的生理学、OSA综合征的治疗及其在勃起和性功能方面报告的结果相关的文章。已发表的研究表明OSA组中ED的患病率较高。然而，这种对勃起功能的影响是否在OSA的整个严重程度范围内都存在仍不清楚。人们提出了几种假说来解释这种关联的生理机制。在大多数研究中，持续气道正压通气作为治疗伴有ED的OSA患者的方法，已在性功能参数方面取得了显著改善。按需使用5型磷酸二酯酶抑制剂（iPDE5）对该亚组患者的ED治疗有效，满意度较高。OSA的手术治疗对勃起功能有好处，使用下颌前移装置治疗对性满意度的影响仍不明确。
