从腹泻病例中分离出的非运动性肠侵袭性大肠杆菌中鞭毛的表达与特性分析
Expression and characterization of flagella in nonmotile enteroinvasive Escherichia coli isolated from diarrhea cases.
作者信息
Andrade Agda, Girón Jorge A, Amhaz Juliana M K, Trabulsi Luiz R, Martinez Marina B
机构信息
Departamento de Analises Clinicas e Toxicologicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, Brazil.
出版信息
Infect Immun. 2002 Oct;70(10):5882-6. doi: 10.1128/IAI.70.10.5882-5886.2002.
Abstract
We report that enteroinvasive Escherichia coli (EIEC) serotypes considered to be nonmotile produce an unusually large (77 kDa) flagellin that is assembled into functional flagellum filaments that allow the bacteria to swim in modified motility agar. The EIEC flagellin showed N-terminal identity to most common enterobacterial flagellins, especially those of the E. coli H7 serotype. These data are important in terms of the epidemiology, evolution, and biology of EIEC.
摘要
我们报告称，被认为无运动性的肠侵袭性大肠杆菌（EIEC）血清型产生一种异常大的（77 kDa）鞭毛蛋白，该蛋白组装成功能性鞭毛丝，使细菌能够在改良的运动性琼脂中游动。EIEC鞭毛蛋白在N端与大多数常见肠道细菌鞭毛蛋白具有同一性，尤其是大肠杆菌H7血清型的鞭毛蛋白。这些数据在EIEC的流行病学、进化和生物学方面具有重要意义。
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